Cancer Care

A 7-year-old girl presented with persistent pain in the right knee for two months. Initial investigations, including X-ray and MRI, raised suspicion of a malignant lesion in the distal femur near the knee joint.

A biopsy confirmed the diagnosis of osteosarcoma, a rare bone malignancy seen in children and adolescents. A metastatic workup was conducted to assess disease spread, which showed no evidence of metastasis.

The patient was initiated on a structured treatment protocol involving multiple cycles of neoadjuvant chemotherapy, followed by planned surgical intervention and postoperative chemotherapy.

After completion of four chemotherapy cycles, repeat imaging demonstrated a favorable response, and surgical management was undertaken. Considering the child’s age and significant remaining growth potential, the key challenge was to achieve oncological clearance while preserving future limb growth.

A customised expandable prosthesis was designed for the patient to accommodate longitudinal bone growth through future length adjustments. The surgical procedure was completed successfully, and the postoperative course remained stable and uneventful.

The patient continues under follow-up, with the focus on long-term recovery, functional preservation, and support for normal growth and development.
 

Treatment By:
Dr. Nikhil Tandon

A patient with a long-standing history of lymphedema in her right arm since 2014 presented with persistent swelling and concerning changes in the affected limb. Clinical evaluation and further investigations, including PET scan and FNAC, confirmed the presence of a rare and aggressive malignancy involving the cutaneous and subcutaneous tissues of the forearm, diagnosed as lymphangiosarcoma.

Given the complexity of the condition and the risk to limb function, a carefully planned, patient-centric treatment approach was undertaken under the care of Dr. Manish Singhal, Vice Chairman – Medical Oncology, Yashoda Institute of Cancer Care.

The patient was treated with a combination of advanced chemotherapy and targeted therapy. The treatment was precisely tailored to control disease progression while prioritising limb preservation.

She responded well to therapy, with effective disease control achieved without the need for amputation. The limb was successfully preserved, maintaining both function and quality of life.

This case highlights the role of precision oncology and timely intervention in managing rare and challenging cancers, demonstrating how advanced treatment strategies can achieve optimal outcomes while preserving function and improving patient well-being.

Treatment By:
Dr. Manish Singhal

A 78-year-old male patient presented with difficulty in swallowing and a small growth at the base of the tongue. Initial evaluation, including biopsy and imaging, confirmed a malignancy involving the tongue along with an affected lymph node in the neck.

As part of routine staging, a whole-body scan revealed an additional lesion in the upper lobe of the lung with associated chest lymph nodes. Further evaluation confirmed this to be a second, unrelated primary cancer. This rare presentation of two simultaneous primary cancers required a carefully coordinated and highly specialised treatment approach.

After a detailed assessment by a multidisciplinary team, a comprehensive treatment plan was developed with curative intent. The patient was treated using advanced adaptive radiotherapy, a technique that allows real-time adjustments to radiation delivery based on daily imaging and anatomical changes, ensuring high precision and safety.

Both cancers were treated concurrently. The lung and chest lymph nodes received a planned course of radiation over six weeks, while the tongue and neck region were treated over seven weeks. Each session was guided by high-resolution imaging, enabling accurate targeting of the tumours while preserving surrounding healthy structures. The patient completed the treatment successfully with good tolerance. He showed a steady recovery and continues to remain stable on follow-up.

This case highlights the power of advanced radiation technology and multidisciplinary expertise in managing rare and complex cancer presentations.
 

Treatment By:
Dr. Gagan Saini

A 55-year-old woman diagnosed with advanced high-grade serous ovarian cancer presented after completing three cycles of neoadjuvant chemotherapy. She had responded well to treatment, with imaging showing significant disease resolution and tumour markers returning to normal levels. Following a comprehensive evaluation, she was planned for interval debulking surgery combined with Heated Intraperitoneal Chemotherapy (HIPEC).

After detailed counselling and preoperative optimisation, the patient underwent surgery under the care of the expert team. A meticulous cytoreductive procedure was performed to remove all visible disease, followed by the administration of HIPEC, a targeted chemotherapy delivered directly into the abdominal cavity using specialised equipment over a controlled duration. The entire procedure was carried out with precise monitoring and a highly coordinated approach.

Postoperatively, the patient was closely monitored with a structured care protocol, including optimal fluid management and regular assessment of clinical parameters to support recovery.

The patient demonstrated a smooth and steady recovery and was discharged in stable condition on the eighth postoperative day. She continues to do well on follow-up.

This case marks a significant milestone as one of the successful HIPEC procedures performed at Yashoda Medicity, highlighting the team’s expertise in delivering advanced oncological care with precision and safety.

Treatment By:
Dr. Satinder Kaur, Dr. Hemlata Garg, and Dr. Ipshita Sahoo

A 30-year-old woman presented with abdominal fullness and on/off pain for the last 3 months, without any menstrual concerns. Imaging revealed a large abdomino-pelvic mass with multiple nodular growths extending into the abdomen, suggestive of a rare condition where multiple fibroids are spread across the abdominal cavity and involve surrounding organs.

After detailed evaluation and counselling, a surgical plan was carefully designed with a strong focus on preserving her fertility. The patient underwent exploratory surgery under the care of the expert team.

During the procedure, multiple fibroids of varying sizes were identified arising from the uterus and extending into the pelvic and upper abdominal regions. A highly precise and carefully controlled surgical approach was adopted to safely remove the fibroids while preserving the uterus and both ovaries.

The surgery lasted approximately five hours, during which 15 fibroids weighing nearly 3 kg were successfully removed with minimal blood loss. The uterus and both ovaries were preserved, maintaining the patient’s reproductive potential.

The patient had a smooth recovery and was discharged in stable condition. This case highlights the team’s expertise in managing rare and complex conditions with a focus on precision, safety, and organ preservation, ensuring the best possible outcome for the patient.

Treatment By:
Dr. Satinder Kaur, Dr. Hemlata Garg, and Dr. Ipshita Sahoo