Both these methods work together to eliminate the main factors responsible for metabolic syndrome, i.e., insulin resistance and chronic inflammation. Drug treatment smooths out the hormonal changes, and on the other hand, lifestyle changes, such as planned physical exercises and eating in accordance with medical nutrition therapy, lead to a gradual and long-term weight loss. As a result, they lower blood pressure, improve lipid profiles, and greatly reduce the risk of developing Type 2 diabetes or heart disease.