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Renal transplantation is the treatment of choice for patients with kidney failure, offering long-term recovery, improved survival, and enhanced quality of life. At Yashoda Medicity, our Renal Transplant Program is equipped to manage even the most complex transplant cases, ensuring safe and successful outcomes through advanced surgical techniques and multidisciplinary expertise.
Our transplant unit specializes in handling:
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Senior Director: Urology, Uro-Oncology, Robotics & Renal Transplant
Associate Director – Urology, Uro-oncology, Robotics & Renal Transplant
Senior Consultant - Nephrology & Renal Transplant
Senior Consultant – Nephrology & Renal Transplant
A challenging Case of renal transplant with a history of >22 units of blood transfusion and class 1 DSA positive
A 26-year-old male was diagnosed with chronic kidney disease after developing generalised weakness and loss of appetite. Investigations revealed impaired renal function with a creatinine of 12 mg/dl and haemoglobin of 5 g/dl. He was started on haemodialysis through a catheter placed in the right side of his neck and advised AV fistula creation with maintenance haemodialysis three times a week.
Despite regular dialysis, his anaemia persisted and he required multiple blood transfusions...
A challenging Case of renal transplant with a history of >22 units of blood transfusion and class 1 DSA positive
A 26-year-old male was diagnosed with chronic kidney disease after developing generalised weakness and loss of appetite. Investigations revealed impaired renal function with a creatinine of 12 mg/dl and haemoglobin of 5 g/dl. He was started on haemodialysis through a catheter placed in the right side of his neck and advised AV fistula creation with maintenance haemodialysis three times a week.
Despite regular dialysis, his anaemia persisted and he required multiple blood transfusions (more than 22 units over three months) even while receiving erythropoietin and iron therapy. Anaemia workup revealed occult blood in the stool, and upper GI endoscopy confirmed peptic ulcer disease.
He consulted our team of nephrologists (Dr Prajit Mazumdar and Dr Inderjit G. Momin) and urologists (Dr Vaibhav Saxena and Dr Kuldeep Agarwal) at Yashoda Superspeciality Hospitals, Kaushambi, where renal transplantation was advised. His mother, who had a matching blood group, was identified as the donor. However, transplant workup revealed donor-specific antibodies on single antigen bead testing (Class I) with an MFI greater than 2500 on multiple beads, most likely due to the multiple blood transfusions. This significantly increased the risk of acute rejection in the immediate post-transplant period, making the case high-risk.
After thorough counselling regarding risks, he underwent desensitisation with two sessions of plasmapheresis and IVIg to reduce the donor-specific antibodies. He then successfully underwent renal transplantation with ATG induction. Post-transplant, he maintained good urine output with steadily improving creatinine levels and was discharged with a creatinine of 1.2 mg/dl.
He continues to do well on outpatient follow-up.
Treatment By:
Dr Prajit Mazumdar, Dr Inderjit G. Momin, Dr Vaibhav Saxena, and Dr Kuldeep Agarwal
Mr. Ajeet Kumar Verma from Yashoda Homecare provided satisfactory service of sample collection. Well behaved, humble & polite person
“I had really good experience with Yashoda Home Care, the sample collection was very hygienically taken and pain-free, hassle-free. Mr. Ajeet was the phlebotomist.”
Had a good experience with Ajeet Kumar Verma from Yashoda Home Care who supported me while I was looking for someone to dress my mom’s stitches. He is very professional and a caring person.
Great support and service by the Home care department. Everyone from Ms Niharika, Mr. Anoop to all the attendants including Mr. Natwar Pandey, Mr Inam and Mr. Ajit, all have been superbly supportive and helpful throughout. God bless you all and highly recommended.
Very good services in home care Yashoda hospital his ish
Caretaker Deepanshu and Jatin and Satish is very good caretaker I have never seen better care takers in my life.
And he is very polite behaviour and friend in nature
Yashoda hospital Kaushambi service is very good according other hospital and other home care services
The home care facility provided by the hospital is also good, the staff which was at home was cooperative.
Home care services are Good. Mr. सुनील Sajwan was cooperative and the केयर taker Mrs. Shushila's वर्क has been quite satisfactory.
Had a. Very good experience with Yashoda Homecare, Kaushambi. The staff was very cooperative with excellent on time services. I would like to give a special mention to Mr Sunil Sajwan (Sales) and Sushila ji (PCA) for their quick response and excellent services.
Fully satisfied Mr .Ajeet Kumar Verma service Yashoda home care . vry good
Was great to recieve the best homecare services from yashoda hospital and really impressed with Ms. Niharika's support at the initial phase followed by Mr. Natwar Pandey who was really supportive in taking care of my father basic daily needs.
Thanks for all the support
